Algae, Tree, Herbs, Bush, Shrub, Grasses, Vines, Fern, Moss, Spermatophyta, Bryophyta, Fern Ally, Flower, Photosynthesis, Eukaryote, Prokaryote, carbohydrate, vitamins, amino acids, botany, lipids, proteins, cell, cell wall, biotechnology, metabolities, enzymes, agriculture, horticulture, agronomy, bryology, plaleobotany, phytochemistry, enthnobotany, anatomy, ecology, plant breeding, ecology, genetics, chlorophyll, chloroplast, gymnosperms, sporophytes, spores, seed, pollination, pollen, agriculture, horticulture, taxanomy, fungi, molecular biology, biochemistry, bioinfomatics, microbiology, fertilizers, insecticides, pesticides, herbicides, plant growth regulators, medicinal plants, herbal medicines, chemistry, cytogenetics, bryology, ethnobotany, plant pathology, methodolgy, research institutes, scientific journals, companies, farmer, scientists, plant nutrition
Select Language:
Main Menu
Please click the main subject to get the list of sub-categories
Services offered
  Section: Molecular Biology of Plant Pathways » Enzyme Engineering
Please share with your friends:  


Adams, K. L., Cronn, R., Percifield, R., and Wendel, J. F. (2003). Genes duplicated by polyploidy show unequal contributions to the transcriptome and organ-specific reciprocal silencing. Proc. Natl. Acad. Sci. USA 100, 4649–4654.

Aguinaldo, A. M., and Arnold, F. H. (2003). Staggered extension process (StEP) in vitro recombination. Methods Mol. Biol. 231, 105–110.

Altamirano, M. M., Blackburn, J. M., Aguayo, C., and Fersht, A. R. (2000). Directed evolution of new catalytic activity using the alpha/beta-barrel scaffold. Nature 403, 617–622.

Arnold, F. H. (1998). When blind is better: Protein design by evolution. Nat. Biotechnol. 16, 617–618.

Arnold, F. H. (2001). Combinatorial and computational challenges for biocatalyst design. Nature 409, 253–257.

Ballicora, M. A., Iglesias, A. A., and Preiss, J. (2003). ADP-glucose pyrophosphorylase, a regulatory enzyme for bacterial glycogen synthesis. Microbiol. Mol. Biol. Rev. 67, 213–225, table of contents.

Broadwater, J. A., Whittle, E., and Shanklin, J. (2002). Desaturation and hydroxylation. Residues 148 and 324 of Arabidopsis FAD2, in addition to substrate chain length, exert a major influence in partitioning of catalytic specificity. J. Biol. Chem. 277, 15613–15620.

Broun, P., Boddupalli, S., and Somerville, C. (1998). A bifunctional oleate 12-hydroxylase: Desaturase from Lesquerella fendleri. Plant J. 13, 201–210.

Cadwell, R. C., and Joyce, G. F. (1992). Randomization of genes by PCR mutagenesis. PCR Methods Appl. 2, 28–33.

Cahoon, E. B., and Shanklin, J. (2000). Substrate-dependent mutant complementation to select fatty acid desaturase variants for metabolic engineering of plant seed oils. Proc. Natl. Acad. Sci. USA 97, 12350–12355.

Cahoon, E. B., Carlson, T. J., Ripp, K. G., Schweiger, B. J., Cook, G. A., Hall, S. E., and Kinney, A. J. (1999). Biosynthetic origin of conjugated double bonds: Production of fatty acid components of high-value drying oils in transgenic soybean embryos. Proc. Natl. Acad. Sci. USA 96, 12935–12940.

Covello, P. S., and Reed, D. W. (1996). Functional expression of the extraplastidial Arabidopsis thaliana oleate desaturase gene (FAD2) in Saccharomyces cerevisiae. Plant Physiol. 111, 223–236.

Clark, D. P., Demendoza, D., Polacco, M. L., and Cronan, J. E., Jr. (1983). Beta-hydroxydecanoyl thio ester dehydrase does not catalyze a rate-limiting step in Escherichia coli unsaturated fatty acid synthesis. Biochemistry 22, 5897–5902.

Crameri, A., Cwirla, S., and Stemmer, W. P. (1996). Construction and evolution of antibody-phage libraries by DNA shuffling. Nat. Med. 2, 100–102.

Crameri, A., Dawes, G., Rodriguez, E., Jr., Silver, S., and Stemmer, W. P. (1997). Molecular evolution of an arsenate detoxification pathway byDNAshuffling [see comments]. Nat. Biotechnol. 15, 436–438.

Crameri, A., Raillard, S. A., Bermudez, E., and Stemmer, W. P. (1998). DNA shuffling of a family of genes from diverse species accelerates directed evolution. Nature 391, 288–291.

Dahiyat, B. I., and Mayo, S. L. (1997). De novo protein design: Fully automated sequence selection. Science 278, 82–87.

Desantis, G., Wong, K., Farwell, B., Chatman, K., Zhu, Z., Tomlinson, G., Huang, H., Tan, X., Bibbs, L., Chen, P., Kretz, K., Burk, M. J., et al. (2003). Creation of a productive, highly enantioselective nitrilase through gene site saturation mutagenesis (GSSM). J. Am. Chem. Soc. 125, 11476–11477.

Dyer, J. M., Chapital, D. C., Kuan, J. C., Mullen, R. T., Turner, C., Mckeon, T. A., and Pepperman, A. B. (2002). Molecular analysis of a bifunctional fatty acid conjugase/desaturase from tung. Implications for the evolution of plant fatty acid diversity. Plant Physiol. 130, 2027–2038.

Facciotti, M. T., Bertain, P. B., and Yuan, L. (1999). Improved stearate phenotype in transgenic canola expressing a modified acyl-acyl carrier protein thioesterase. Nat. Biotechnol. 17, 593–597.

Farinas, E. T., Bulter, T., and Arnold, F. H. (2001). Directed enzyme evolution. Curr. Opin. Biotechnol. 12, 545–551.

Force, A., Lynch, M., Pickett, F. B., Amores, A., Yan, Y. L., and Postlethwait, J. (1999). Preservation of duplicate genes by complementary, degenerative mutations. Genetics 151, 1531–1545.

Fox, R., Roy, A., Govindarajan, S., Minshull, J., Gustafsson, C., Jones, J. T., and Emig, R. (2003). Optimizing the search algorithm for protein engineering by directed evolution. Protein Eng. 16, 589–597.

Gao, C., Lin, C. H., Lo, C. H. L., Mao, S., Wirsching, P., Lerner, R. A., and Janda, K. D. (1997). Making chemistry selectable by linking it to infectivity. Proc. Natl. Acad. Sci. USA 94, 11777–11782.

Gerlt, J. A., and Babbitt, P. C. (2001). Divergent evolution of enzymatic function: Mechanistically diverse superfamilies and functionally distinct suprafamilies. Annu. Rev. Biochem. 70, 209–246.

Graham, I. A., Li, Y., and Larson, T. R. (2002). Acyl-CoA measurements in plants suggest a role in regulating various cellular processes. Biochem. Soc. Trans. 30, 1095–1099.

Gray, K. A., Richardson, T. H., Robertson, D. E., Swanson, P. E., and Subramanian, M. V. (2003). Soilbased gene discovery: A new technology to accelerate and broaden biocatalytic applications. Adv. Appl. Microbiol. 52, 1–27.

Hobohm, U., and Sander, C. (1995). A sequence property approach to searching protein databases. J. Mol. Biol. 251, 390–399.

Joo, H., Arisawa, A., Lin, Z., and Arnold, F. H. (1999). A high-throughput digital imaging screen for the discovery and directed evolution of oxygenases. Chem. Biol. 6, 699–706.

Kempin, S. A., Savidge, B., and Yanofsky, M. F. (1995). Molecular basis of the cauliflower phenotype in Arabidopsis. Science 267, 522–525.

Merz, A., Yee, M. C., Szadkowski, H., Pappenberger, G., Crameri, A., Stemmer, W. P., Yanofsky, C., and Kirschner, K. (2000). Improving the catalytic activity of a thermophilic enzyme at low temperatures. Biochemistry 39, 880–889.

Meyer, M. M., Silberg, J. J., Voigt, C. A., Endelman, J. B., Mayo, S. L., Wang, Z. G., and Arnold, F. H. (2003). Library analysis of SCHEMA-guided protein recombination. Protein Sci. 12, 1686–1693.

Moore, J. C., and Arnold, F. H. (1996). Directed evolution of a para-nitrobenzyl esterase for aqueousorganic solvents. Nat. Biotechnol. 14, 458–467.

Naki, D., Paech, C., Granshaw, G., and Schellenberger, V. (1998). Selection of a subtillisinhyperproducing Bacillus in a highly structured environment. Appl. Microbiol. Biotechnol. 49, 290–294.

Ness, J. E., Kim, S., Gottman, A., Pak, R., Krebber, A., Borchert, T. V., Govindarajan, S., Mundorff, E. C., and Minshull, J. (2002). Synthetic shuffling expands functional protein diversity by allowing amino acids to recombine independently. Nat. Biotechnol. 20, 1251–1255.

Nowak, W., Gawlowska, M., Jarmolowski, A., and Augustyniak, J. (2001). Effect of nuclear matrix attachment regions on transgene expression in tobacco plants. Acta Biochim. Pol. 48, 637–646.

Otey, C. R., Silberg, J. J., Voigt, C. A., Endelman, J. B., Bandara, G., and Arnold, F. H. (2004). Functional evolution and structural conservation in chimeric cytochromes p450: Calibrating a structure-guided approach. Chem. Biol. 11, 309–318.
Poirier, Y. (2001). Production of polyesters in transgenic plants. Adv. Biochem. Eng. Biotechnol. 71, 209–240.

Powell, K. A., Ramer, S. W., Del Cardayre, S. B., Stemmer, W. P., Tobin, M. B., Longchamp, P. F., and Huisman, G. W. (2001). Directed evolution and biocatalysis. Angew. Chem. Int. Ed. Engl. 40, 3948–3959.

Preiss, J. (1996). ADPglucose pyrophosphorylase: Basic science and applications in biotechnology. Biotechnol. Annu. Rev. 2, 259–279.

Reetz, M. T., Zonta, A., Schimossek, K., Liebeton, K., and Jaeger, K. E. (1997). Creation of enantioselective biocataalysts for organic chemistry by in vitro evolution. Angew. Chem. Int. Ed. Engl. 36, 2830–2833.

Schwender, J., Goffman, F., Ohlrogge, J. B., and Shachar-Hill, Y. (2004a). RuBisCO without the Calvin cycle improves the carbon efficiency of developing green seeds. Nature 432, 779–782.

Schwender, J., Ohlrogge, J., and Shachar-Hill, Y. (2004b). Understanding flux in plant metabolic networks. Curr. Opin. Plant Biol. 7, 309–317.

Shafikhani, S., Siegel, R. A., Ferrari, E., and Schellenberger, V. (1997). Generation of large libraries of random mutants in Bacillus subtilis by PCR-based plasmid multimerization. Biotechniques 23, 304–310.

Shanklin, J., and Cahoon, E. B. (1998). Desaturation and related modifications of fatty acids. Annu. Rev. Plant Physiol. Plant Mol. Biol. 49, 611–641.

Stemmer, W. P. (1994a). DNA shuffling by random fragmentation and reassembly: In vitro recombination for molecular evolution. Proc. Natl. Acad. Sci. USA 91, 10747–10751.

Stemmer, W. P. (1994b). Rapid evolution of a protein in vitro by DNA shuffling. Nature 370, 389–391.

Stuitje, A. R., Verbree, E. C., Van Der Linden, K. H., Mietiewska, E. M., Nap, J. P., and Kneppers, T. J. A. (2003). Seed-expressed fluorescent proteins as versatile tools for easy (co)transformation and highthroughput functional genomics in Arabidopsis. Plant Biotechnol. J. 1, 301–309.

Sweetlove, L. J., and Fernie, A. R. (2005). Regulation of metabolic networks: Understanding metabolic complexity in the systems biology era. New Phytol. 168, 9–24.

Taverna, D. M., and Goldstein, R. A. (2002a). Why are proteins so robust to site mutations? J. Mol. Biol. 315, 479–484.

Taverna, D. M., and Goldstein, R. A. (2002b). Why are proteins marginally stable? Proteins 46, 105–109.

Thelen, J. J., and Ohlrogge, J. B. (2002). Metabolic engineering of fatty acid biosynthesis in plants. Metab. Eng. 4, 12–21.

Voigt, C. A., Martinez, C., Wang, Z. G., Mayo, S. L., and Arnold, F. H. (2002). Protein building blocks preserved by recombination. Nat. Struct. Biol. 9, 553–558.

Whittle, E., Cahoon, E. B., and Shanklin, J. (2001). Engineering delta 9–16:0-acyl carrier protein (ACP) desaturase specificity based on combinatorial saturation mutagenesis and logical redesign of the castor delta 9–18:0-ACP desaturase. J. Biol. Chem. 276, 21500–21505.

You, L., and Arnold, F. H. (1996). Directed evolution of subtilisin E in Bacillus subtilis to enhance total activity in aqueous dimethylformamide. Protein Eng. 9, 77–83.

Zhang, C., and Delisi, C. (1998). Estimating the number of protein folds. J. Mol. Biol. 284, 1301–1305.

Zhang, J. H., Dawes, G., and Stemmer, W. P. (1997). Directed evolution of a fucosidase from a galactosidase by DNA shuffling and screening. Proc. Natl. Acad. Sci. USA 94, 4504–4509.

Zhang, Y. X., Perry, K., Vinci, V. A., Powell, K., Stemmer, W. P., and Del Cardayre, S. B. (2002). Genome shuffling leads to rapid phenotypic improvement in bacteria. Nature 415, 644–646.

Zhao, H., and Arnold, F. H. (1999). Directed evolution converts subtilisin E into a functional equivalent of thermitase. Protein Eng. 12, 47–53.


Copyrights 2012 © | Disclaimer