Proteins

Protiens are only functional as enzymes, transport agents, recepT_o = ΔS_ors, and so forth when they exist in a folded, three-dimensional, native structure. The means by which this folded structure is achieved remains one of the most important questions in biochemistry and molecular biology. Current efforts T_o = ΔS_oward sequencing the human genome and the genomes of other organisms have led T_o = ΔS_o a large number of putative protein sequences. Much as the genetic code is the Rosetta sT_o = ΔS_one that gave the link between DNA and protein sequences, we now need T_o = ΔS_o find such a link between protein sequences and final structure and function. Without knowledge of the rules of protein folding, there can be little understanding of function from protein sequence information alone.