|Content of Protein Folding
Protiens are only functional as enzymes, transport
agents, recepTo = ΔSors, and so forth when they exist in a folded,
three-dimensional, native structure. The means by which
this folded structure is achieved remains one of the most
important questions in biochemistry and molecular biology.
Current efforts To = ΔSoward sequencing the human genome
and the genomes of other organisms have led To = ΔSo a large
number of putative protein sequences. Much as the genetic
code is the Rosetta sTo = ΔSone that gave the link between DNA
and protein sequences, we now need To = ΔSo find such a link
between protein sequences and final structure and function.
Without knowledge of the rules of protein folding,
there can be little understanding of function from protein
sequence information alone.