References
Selected References
Cavenee, W. K., and R. L. White. 1995. The genetic basis of cancer. Sci. Am. 272:72–79 (Mar.). Describes mutations in cells of colorectal cancer and brain tumors.
Culotta, D., and D. E. Koshland, Jr. 1993. p53 sweeps through cancer research. Science 262:1958–1961. p53 was discovered in 1979, but it was 10 years before scientists began to uncover its importance.
Erlich, H. A., D. Gelfand, and J. J. Sninsky. 1991. Recent advances in the polymerase chain reaction. Science 252:1643–1651. A review of recent developments in methods and applications of the PCR.
Friend, S. 1994. p53: a glimpse at the puppet behind the shadow play. Science 265:334–335. A short summary of the crucial roles of p53 protein and how mutations in the gene coding for it lead to inactivation.
Hall, A. 1994. A biochemical function for Ras— at last. Science 264:1413–1414. Ras protein is an enzyme in a signal transduction cascade stimulating a cell to divide.
Hieter, P., and M. Boguski. 1997. Functional genomics: it’s all how you read it. Science 278:601–602. An explanation of functional genomics.
Klug, W. S. 1991. Concepts of genetics, ed. 3. New York, Macmillan Publishing Company. A shorter text.
Koshland, D. E., Jr. 1989. The engineering of species. Science 244:1233. This is the lead editorial in an issue of the journal containing several reviews on genetic engineering.
Mange, E. J., and A. P. Mange. 1999. Basic human genetics, ed. 2 Sunderland, Massachusetts, Sinauer Associates. A readable, introductory text concentrating on the genetics of the animal species of greatest concern to most of us.
Marx, J. 1994. Oncogenes reach a milestone. Science 266:1942–1944. Research on oncogenes has helped us understand many normal cell processes.
Mullikin, J. C., and A. A. McMurray. 1999. Sequencing the genome, fast. Science 283:1867–1868. A report from the Sanger Centre in England on their schedule for sequencing the human genome.
Mullis, K. B. 1990. The unusual origin of the polymerase chain reaction. Sci. Am. 262:56–65 (Apr.). How the author had the idea for the simple production of unlimited copies of DNA while driving through the mountains of California.
Russell, P. J. 1992. Genetics, ed. 3. New York, HarperCollins Publishers. Popular general genetics text.
Schuler, G. D., and 113 others. 1996. A gene map of the human genome. Science 274:540–546. More than 16,000 human genes had been mapped when this paper was published, representing perhaps onefifth of the total.
Verma, I. M. 1990. Gene therapy. Sci. Am. 263:68–84 (Nov.). A review of prospects for treating and preventing genetic diseases by putting healthy genes into the body.
Weinberg, R. A. 1991. Tumor suppressor genes. Science 254:1138–1146. How inactivation of tumor suppressor genes is a step in production of cancer.
Cavenee, W. K., and R. L. White. 1995. The genetic basis of cancer. Sci. Am. 272:72–79 (Mar.). Describes mutations in cells of colorectal cancer and brain tumors.
Culotta, D., and D. E. Koshland, Jr. 1993. p53 sweeps through cancer research. Science 262:1958–1961. p53 was discovered in 1979, but it was 10 years before scientists began to uncover its importance.
Erlich, H. A., D. Gelfand, and J. J. Sninsky. 1991. Recent advances in the polymerase chain reaction. Science 252:1643–1651. A review of recent developments in methods and applications of the PCR.
Friend, S. 1994. p53: a glimpse at the puppet behind the shadow play. Science 265:334–335. A short summary of the crucial roles of p53 protein and how mutations in the gene coding for it lead to inactivation.
Hall, A. 1994. A biochemical function for Ras— at last. Science 264:1413–1414. Ras protein is an enzyme in a signal transduction cascade stimulating a cell to divide.
Hieter, P., and M. Boguski. 1997. Functional genomics: it’s all how you read it. Science 278:601–602. An explanation of functional genomics.
Klug, W. S. 1991. Concepts of genetics, ed. 3. New York, Macmillan Publishing Company. A shorter text.
Koshland, D. E., Jr. 1989. The engineering of species. Science 244:1233. This is the lead editorial in an issue of the journal containing several reviews on genetic engineering.
Mange, E. J., and A. P. Mange. 1999. Basic human genetics, ed. 2 Sunderland, Massachusetts, Sinauer Associates. A readable, introductory text concentrating on the genetics of the animal species of greatest concern to most of us.
Marx, J. 1994. Oncogenes reach a milestone. Science 266:1942–1944. Research on oncogenes has helped us understand many normal cell processes.
Mullikin, J. C., and A. A. McMurray. 1999. Sequencing the genome, fast. Science 283:1867–1868. A report from the Sanger Centre in England on their schedule for sequencing the human genome.
Mullis, K. B. 1990. The unusual origin of the polymerase chain reaction. Sci. Am. 262:56–65 (Apr.). How the author had the idea for the simple production of unlimited copies of DNA while driving through the mountains of California.
Russell, P. J. 1992. Genetics, ed. 3. New York, HarperCollins Publishers. Popular general genetics text.
Schuler, G. D., and 113 others. 1996. A gene map of the human genome. Science 274:540–546. More than 16,000 human genes had been mapped when this paper was published, representing perhaps onefifth of the total.
Verma, I. M. 1990. Gene therapy. Sci. Am. 263:68–84 (Nov.). A review of prospects for treating and preventing genetic diseases by putting healthy genes into the body.
Weinberg, R. A. 1991. Tumor suppressor genes. Science 254:1138–1146. How inactivation of tumor suppressor genes is a step in production of cancer.
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